ASEA Health Benefits
Healthy cells begin with...
Redox Metabolism + Cell Communication
In many ways, these inter-linked processes are the foundation for all other ASEA health benefits! Metabolism is how our bodies maintain life. It is what allows our cells to carry out their daily functions, and adapt to changes when necessary. This process involves networks of biochemical reactions, that are finely tuned to suit the needs of healthy cells.
But metabolism only works because of redox signaling molecules (ROS)! These naturally-produced molecules act as chemical signals to regulate metabolism; they notify our cells to update their metabolic activities, in response to the environment. Thus ROS function as messengers, sustaining cellular communication throughout the body, and across many biological pathways in a cascade effect.
ASEA replenishes ROS
Research has revealed that some people may not generate enough redox signaling molecules. This can be due to genetic conditions, or behavioral and environmental changes. If you’ve noticed a decrease in energy, or longer recovery times, it could be a result of insufficient ROS. ASEA health product contains trillions of redox signaling molecules– to restore cellular communication, and have you functioning at your best!
ASEA Benefits: 10 Years of Personal Experience
My first breakthrough came after drinking ASEA Redox for about two weeks. One night I was driving through town and was surprised by the joy of seeing clearly all the neon signs and the street lights! These objects used to be blurry and streaky when I drove at night. Now lights are clear, lines are crisp.
Nothing else in my routine had changed, so the new ASEA drink seemed to make the difference for me! These days, I even use ASEA Redox as eye drops. It works to soothe my eyes whenever they feel dry, and keeps them healthy. Slowly, even black floaters disappear.
After drinking ASEA Redox for 6 months, I’ve experienced near total relief, and have been living a good life with minimal allergies. My immune system must have become so much stronger. My inflammatory responses better regulated.
There was a time I thought I could do without ASEA, and I stopped drinking it for several months. Then my nose started running again… and my experiment came to an end. So yes, your body seems to tell you when you stop drinking ASEA Redox for an extended period of time.
Alleviated Stomach Aches
I was sensitive to gluten. Accidentally when I ate the wrong food I would have painful upheavals to my stomach. I would lie down for hours without a relief. One day while suffering through stomach pains, I decided to try 4oz of ASEA Redox. In 5-10 minutes my pain subsided! Incidents like this happened many times. Eventually after years of drinking ASEA Redox, I have overcome my gluten sensitivity, and I can eat anything I want.
Reduced Muscle and Joint Pain
Aging is real… muscle aches and joint pain begin to creep up on me now! I consulted various doctors for arthritus, but did not want to take drugs that have side effects. So far by consistently drinking ASEA, and consciously eliminating foods that cause inflammation in my body, I haven’t needed to seek arthritis medication. I also added the ASEA VIA Omega Fatty Acids to my diet, plus exercise every day. So far so good, aging is manageable!
Sleeping Through the Night
Many have tried ASEA Redox simply because it helps to improve sleep quality. Most of the time, I’m able to sleep at night after drinking 4oz of ASEA Redox in the morning on an empty stomach. But occasionally, life is extra stressful, and I find my mind racing! That’s when I drink another 2oz right before bed. This helps me fall asleep quickly and stay asleep, without interruptions. Magnesium supplements also work well with ASEA to keep me rested.
Going Nap-Free
For a long time, usually by 4pm in the afternoon I would be quite dead and must take a nap to get by. After drinking ASEA Redox for a few months, my energy level was up and up, I walked faster, I could go on without taking a nap! It was very uplifting being able to work without tiredness holding me back, and to feel good about achieving what I want in life!
Mental Clarity
For working professionals with a demanding job, ASEA is a definite help in providing mental clarity that is so needed to achieve good performance. I can say I am happy with my mental clarity, I have never experienced brain fog or mental fatigue since taking ASEA Redox.
I love the ASEA skin products!! The ASEA facial wash and toner give me a clean and refreshing feeling, the serum works wonders on my face, the moisturizer is a must for everyday use.
In the evening I use ASEA Renu as a base for my facial treatment and I apply facial oil on top of it. This makes my skin stay hydrated and nourished to maintain a youthful look. The amazing thing is ASEA Renu can act as a therapeutic gel, because it easily soothes skin problems and effectively treats skin irritations like no other cream or gel I’ve tried.
Health Benefits from Scientific Research!
Production of redox signaling molecules (or ROS) is largely from within white blood cells— and for good reason! White blood cells are immune system cells that track down foreign invaders (including bacteria and viruses), and instigate the body’s fight against infection. They do so by releasing ROS in what is called a respiratory burst.
The sudden burst of ROS is able to 1) kill pathogens directly by oxidizing and damaging them, and 2) initiate redox signaling to activate more white blood cells, so they can group together, and defend the body in a coordinated effort. Redox signaling molecules also alert cells to remove damaged structures, and begin tissue repairs.
Because ROS are such important regulators for inflammatory and immune responses, people who suffer from ROS deficiency are particularly succeptible to infections and disease.
※ Forman, Henry Jay, and Martine Torres. “Reactive Oxygen Species and Cell Signaling.” American Journal of Respiratory and Critical Care Medicine, vol. 166, no. supplement_1, 15 Dec. 2002, pp. S4–S8. ATS Journals, https://doi.org/10.1164/rccm.2206007.
Recently, studies have indicated that when our hearts need to beat faster, redox signaling molecules are released to facilitate this. Whether from normal exercise, or from cardiac conditions, elevated heart rate occurs because ROS can control the contraction speeds of cardiac muscles.
By signaling our cells to modify excitation-contraction pathways, ROS enable the quicker release of calcium in cardiac muscles, allowing our hearts to pump harder, and distribute oxygen quickly throughout the body.
Redox signaling molecules have also been found to support angiogenesis— the formation of new blood vessels, which is a vital part of recovery from tissue injuries.
※ Yang, J. (2019). The role of reactive oxygen species in angiogenesis and preventing tissue injury after brain ischemia. Microvascular Research, 123, 62–67. https://doi.org/10.1016/j.mvr.2018.12.005
Because the food we consume often contains harmful bacteria and pathogens, ROS is consistently produced in the gastrointestinal tract by mucosa-resident cells or immune cells in the area. ROS signal the presence of harmful microbes, and orchestrate the destruction of pathogens through inflammatory responses. Then they activate the pathways needed to heal intestinal wounds.
Insufficient production of ROS in the GI tract has been linked to Crohn’s disease, in which patients suffer chronic inflammation of the gut.
※ Aviello, G., & Knaus, U. (2016). ROS in gastrointestinal inflammation: Rescue Or Sabotage? British Journal of Pharmacology, 174(12), 1704–1718. https://doi.org/10.1111/bph.13428
Stem cells are essential to life because of their unique ability to renew themselves and develop into any cell type, as needed! Unlike other cells in the body, stem cells are capable of replication— or dividing into new cells. They can divide into more stem cells, or differentiated cells with specialized functions.
They are how we transition from a small embryo, into an entire being, with tissues and organs. Additionally, they’re responsible for replacing cells that degrade normally over time, or from injury and disease.
In order to divide, stem cells must be given chemical “go” signals, to activate proliferation pathways; these are redox signaling molecules!
ROS are also required for differentiation. Stem cells from bone marrow need ROS to create fat cells and connective tissue. Meanwhile stem cells from mitochondria need ROS to develop muscle cells.
A few studies found that when ROS levels were lowered, brain, skin, and sperm cells were unable to regenerate. However, they then determined that supplementing H2O2 (a redox signaling molecule) from an external source restored cell regeneration!
※ Schieber, M., & Chandel, N. S. (2014). Ros function in redox signaling and oxidative stress. Current Biology, 24(10), R453–R462. https://doi.org/10.1016/j.cub.2014.03.034
The body has a couple ways of regulating genes and both involve redox signaling molecules! When changes occur in the internal or external environment, the body releases ROS to amplify signals across large distances. This is known as the second messenger system. These signals are often used to direct gene expression.
Genes are sequences of information encoded in DNA that give instructions on protein (and non-protein) production. Therefore, gene expression often describes which proteins are made. Special proteins known as enzymes are used to accelerate/enable chemical reactions in the body. Thus altering the expression of enzymes allows to body to adapt to changes on a genetic level!
Expression can be affected by ROS through transcription, transduction, and through epigenetics. In transcription (the first step in gene expression), ROS signal the pathway to change the way it converts DNA to RNA, which serves as the template of proteins. Then, in transduction, ROS propogate those signals to other cells in the body. Epigenetics is when external factors influence a gene to be turned off entirely, so that certain proteins are no longer made during that time. ROS are used in this case to affect the function of epigenetic enzymes, or by altering the amount of supplies needed.
※ Lennicke, C., & Cochemé, H. M. (2021). Redox metabolism: Ros as specific molecular regulators of cell signaling and function. Molecular Cell, 81(18), 3691–3707. https://doi.org/10.1016/j.molcel.2021.08.018
Cell development— Redox signaling molecules are generated to activate growth factors, which are substances that enable cells to grow and increase in numbers (or proliferate). Thus ROS facilitate the development of cells into tissues, and tissues into organs.
Cell migration— In a study on diabetes patients, researchers discovered that elevated ROS levels were necessary to induce the migration of fibroblasts (cells that form connections to create tissues). Migration of fibroblasts, triggered by redox signaling molecules, is how wounds are able to close, when their cells are able to connect to each other again. Redox controlled cell-adhesion has also been linked to wound repair, cell growth, and embryogenesis.
Natural cell death— Damaged or unwanted cells must be eliminated. Because ROS are involved in signaling natural apoptosis (the process of pre-programmed cell death) some scientists believe ROS could be used to target the death of errant cancer cells.
※ Roy, J., Galano, J., Durand, T., Le Guennec, J., & Chung‐Yung Lee, J. (2017). Physiological role of reactive oxygen species as promoters of natural defenses. The FASEB Journal, 31(9), 3729–3745. https://doi.org/10.1096/fj.201700170r
Increasingly, research suggests that redox signaling molecules regulate metabolic processes that rely on our circadian rhythm. Having adapted to seasonal cycles, as well as the dark/light periods of night/day, our bodies automatically operate on a 24-hour clock known as circadian rhythm.
At different times of day, the amount of ROS produced fluctuates. This ensures that redox signaling molecules activate biological pathways and signal messages at the proper schedule.
※ Lennicke, C., & Cochemé, H. M. (2021). Redox metabolism: Ros as specific molecular regulators of cell signaling and function. Molecular Cell, 81(18), 3691–3707. https://doi.org/10.1016/j.molcel.2021.08.018
Research dating back to the 90s revealed that slightly elevated levels of ROS are found in all muscles cells. This is because ROS are necessary to faciliate contractile movement, and to signal cell adaptation to exercise! With their repair-signaling properties, redox signaling molecules also alert the body of when micro-tears in muscles occur.
Additionally, beyond skeletal muscles, ROS also have purposes for cardiac muscles. As mentioned in the “cardiovascular health” section, ROS are also used to regulate excitation-contraction of heart muscles.
※ Roy, J., Galano, J., Durand, T., Le Guennec, J., & Chung‐Yung Lee, J. (2017). Physiological role of reactive oxygen species as promoters of natural defenses. The FASEB Journal, 31(9), 3729–3745. https://doi.org/10.1096/fj.201700170r
Contrary to previous belief, evidence within the last couple decades has shown that having slightly elevated levels of ROS is essential in preventing accelerated aging. In order to slow down the aging process, our bodies have to maintain tissue health. And because redox signaling molecules have immune and cell repair properties, sufficient ROS is required to extend the life of tissues.
Furthermore, studies conducted on mice and nematodes revealed that those with elevated levels of ROS seemed to live longer than those deficient in ROS. This is attributed to redox signaling molecules activating cellular stress pathways, which in turn protects against the degradation of tissues, and promotes healthy aging, although somewhat counter-intuitively.
※ Shields, H. J., Traa, A., & Van Raamsdonk, J. M. (2021). Beneficial and detrimental effects of reactive oxygen species on lifespan: A comprehensive review of comparative and experimental studies. Frontiers in Cell and Developmental Biology, 9, 1–27. https://doi.org/10.3389/fcell.2021.628157
